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Buffers Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting tonicity. 5. Rheology Fundamentals of rheology- Introduction, types of flow, quantitative measurement of flow, mechanical models to illustrate viscoelasticity, thixotropy, measurement of thixotropy, thixotropy in formulations, rheology of disperse systems, application of rheology to pharmacy. Methods of measuring viscosity. 6. Micromeritics Introduction, importance in Pharmacy, fundamental properties of collection of particles like particle size, particle size distribution, particle shape, particle volume, particle number, surface area, methods for determining particle size, surface area and particle volume. Derived properties of loose powder, flow properties of powders, angle of repose, factors affecting flow of powders. 7. Coarse Dispersions Suspensions - Interfacial properties of suspended particles, settling in suspensions, formulation of suspension. Emulsions- theories of emulsification, physical stability of emulsions, preservation of emulsions, rheologic properties of emulsions, phase equilibria and emulsion formulation. 8. Diffusion and Dissolution Steady state diffusion, procedures and apparatus, dissolution, drug release, diffusion principles in biologic systems, vapor sorption and transmission and thermodynamics of diffusion. PRACTICALS Total Hours 75 Preparation and properties of simple complexes. Design, conduction and reporting of accelerated testing in studying chemical stabilization against hydrolytic decomposition of drugs. Determination of surface and interfacial tension Preparation and properties of colloids. Viscosity determination of Newtonian and Non-Newtonian liquids by one point and multipoint viscometers. Determination of HLB value of surfactant by saponification method. Determination of HLB value by modified Griffin acacia emulsion method. Determination of spreading coefficient of organic liquid by stalagamometer. Determination of particle size by optical method. Determination of particle size by sieving method and efficiency of screening operation. Determination of particle size by sedimentation method using and Andreasson pipette. Determination of flow properties of powder through the tube as a function of length of tube, diameter of orifice of tube and pressure head. Experiments demonstrating the measurement of angle of repose of powders and the factors affecting. Determination of CMC Critical Micelle Concentration of surfactants by surface tension methods. SDS, 150mM sodium chloride, 1mM EDTA, 1mM PMSF, 1mM sodium orthovanadate, complete protease inhibitor cocktail and left on ice for 30min. Then cell homogenates were spun at 13000xg for 15min and supernatants were removed. 40 µg of protein extracts were resolved in 10% SDS-polyacryamide gel and blotted onto nitrocellulose membranes. In 2012, the most expensive states were New York, Hawaii, Texas, Alaska and Wisconsin. The least expensive states were Nevada, Wyoming, Idaho, Colorado and Washington state. Necessity of taking protective measures to reduce contact with mosquitoes protective clothing, insect repellents, mosquito nets, remaining in air-conditioned or well-screened areas. Community Health Systems operates 135 hospitals in 29 states. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of chloroquine to prevent and treat malaria in children. However, safety and efficacy of chloroquine to treat extraintestinal amebiasis have not been established in children. These terms also include proteins that are post-translationally modified through reactions that include glycosylation, acetylation and phosphorylation. Do not take antacids or products containing kaolin within 4 hours before or after taking chloroquine tablets. For the best effect, take this antibiotic at evenly spaced times. To help you remember, take this medication at the same times every day. Unless it is postponed again, Wednesday's vote could decidethe fate of the struggling company. Founder Michael Dell wantsto take it private, arguing that a painful restructuring canbest be performed away from Wall Street's scrutiny.
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Will he really be ready to go in 15 days for the Lakers opener against the Clippers? Jupiter, every 11 days. Treasury says it will reach its borrowinglimit. Publishers, Varanasi. Paper BPH 05 PHARMACEUTICAL CHEMISTRY II INORGANIC MEDICINAL PHARMACEUTICAL CHEMISTRY THEORY Total Teaching Hours: 50 1. Sources of impurities in pharmaceutical substances Importance of limit test and general principles and procedure for limit tests of chloride, sulphate, iron, arsenic, lead and heavy metals. The following topics will be treated covering an outline of methods of preparation, tests for identity, assay procedure and pharmaceutical uses of compounds covered under following headings: 2. Pharmaceutical aids and necessities Acids, bases, buffers, antioxidants, water and pharmaceutically acceptable glass. Veritext should have been sealed. clomid
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